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M9550113.TXT
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1995-03-04
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Document 0113
DOCN M9550113
TI Neuropsychological performance and CD4 levels in HIV-1 asymptomatic
infection.
DT 9505
AU Podraza AM; Bornstein RA; Whitacre CC; Para MF; Fass RJ; Rice RR Jr;
Nasrallah HA; Maine Head Trauma Center Bangor.
SO J Clin Exp Neuropsychol. 1994 Oct;16(5):777-83. Unique Identifier :
AIDSLINE MED/95138241
AB The performance of 68 HIV-1 seropositive asymptomatic (HIV+) subjects
stratified on CD4 levels were compared with 82 HIV-1 seronegative (HIV-)
subjects on a battery of neuropsychological, mood state, and perceived
health status measures. The neuropsychological test battery included
measures of attention, reaction time, memory, intellectual ability,
psychomotor speed, frontal lobe or executive function, and decision
time. None of the HIV+ subjects were taking antiviral agents. The groups
did not differ for age, mood state, or WAIS-R Verbal and Performance IQ
scores. Due to group differences for education and weekly ethanol
consumption, both variables were used as covariates in multivariate
analyses of variance. Relatively few differences were observed between
subgroups of HIV+ patients or between these subgroups and control
subjects. These data suggest that factors other than absolute levels of
immunosuppression as expressed by CD4 levels alone, appear to be
responsible for the deficits observed in HIV+ asymptomatic patients.
DE Adult AIDS Dementia Complex/*DIAGNOSIS/IMMUNOLOGY/PSYCHOLOGY *CD4
Lymphocyte Count Frontal Lobe/PHYSIOPATHOLOGY Human HIV
Seronegativity HIV Seropositivity/*DIAGNOSIS/IMMUNOLOGY/PSYCHOLOGY
HIV-1/*IMMUNOLOGY Longitudinal Studies Male Middle Age
*Neuropsychological Tests/STATISTICS & NUMER DATA Psychometrics
Reference Values Support, U.S. Gov't, P.H.S. JOURNAL ARTICLE
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).